Effect of Cyanoacrylate Adhesive on Tissue Healing After Periodontal Surgery

Background and Aim: Research on reducing the symptoms and discomfort after periodontal surgery is a priority. This study aimed to evaluate the effect of cyanoacrylate adhesive on tissue healing after periodontal surgery. Materials and Methods: In this split-mouth clinical trial, all patients who needed periodontal pocket removal surgery in two or more sextants were examined after receiving written informed consent. The mouth of each patient was randomly divided into control and case groups. Cyanoacrylate adhesive was used in the case group, and sutures were used in the control group to close the wound. Pain, plaque index of the surgical site, and tissue healing were evaluated in the first week of follow-up. The probing depth in the surgical site was assessed at the second follow-up (6 weeks after surgery). All the parameters were statistically analyzed by Mann-U-Whitney test. Results: In the first week of follow-up, the level of pain was 4.7±1.34 in the control group and 4.4±1.68 in the case group with no statistically significant difference (P=0.2). The healing rate was 3.3±0.53 in the control group and 2.7±0.64 in the case group with no statistically significant difference (P=0.3). The plaque index in the first week of follow-up was 3.9±0.82 in the control group and 3.8±0.97 in the case group (P=0.2). The probing depth in the sixth week of follow-up was 2.5±0.67 in the control group and 2.8±0.6 in the case group (P=0.2). Conclusion: Considering the results, it seems that cyanoacrylate adhesive can be a good alternative to sutures, especially when the patient cannot present for suture removal at the appointed time.